Tuesday, July 26, 2005

Quetiapine Seen Safe, Well Tolerated for Bipolar Depression Reuters Health story at Medscape - "Monotherapy with the atypical antipsychotic quetiapine is safe and effective for bipolar depression, according to a report in the July issue the American Journal of Psychiatry. ... 'In an unexpected post hoc analysis, quetiapine was found to be twice as effective as placebo in reducing suicidal thinking, and this improvement was evident as early as the first time point, the end of the first week, and at each and every time point thereafter,' Dr. Calabrese told Reuters Health. 'To my knowledge this is the first time any drug has been shown to have an ability to reduce suicidal thinking in a short-term study of bipolar depression.' " [Viewing Medscape resources requires registration, which is free].