Ethical Dilemmas in Research Integrity
What would you do if faced with a difficult issue in research integrity? There are no right or wrong answers, but your opinion will surely help others to make their best choice. Browse the dilemmas by category and click to respond with your views about each.











 

Selecting a clinical trial site

You are designing the clinical trial for a prosthetic device used when a young child has lost a lower limb.  You wish to conduct the trial overseas, in a region where victums of line mines can be recruited as subjects.  The prosthesis will be very expensive, however, and apart from the high cost of purchase, it will be costly to maintain.  For these reasons, it will almost certainly not be available outside the US.  Is it appropriate to recruit clinical trial subjects from a population that will not benefit from the product?  Is there an obligation to support study participants after the trial ends?

K5R says:  In this situation, although it might be preferable to do the study overseas, logistics prevent it from being performed outside of the US, and so it should be done in the US.  The selection of site for a clinical trial is based on the total sum of information, and benefit by the local population can only be one part of this equation.  There is likely a moral obligation, if not a legal one, to provide some sort of ongoing support for the participants, and this information should be included in the study protocol.


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